MicrobiologyBiochemical JournalPeer-reviewed
Itaconate utilisation by the human pathogen Pseudomonas aeruginosa requires uptake via the IctPQM TRAP transporter
Javeria Mehboob, Reyme Herman, Rory Elston…·Gavin H. Thomas
This study identifies the IctPQM TRAP transporter as essential for Pseudomonas aeruginosa to utilize itaconate, a host-derived metabolite, by showing its specific binding and structural adaptations.
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