Author

Hunter Waltermire

University of PittsburghORCID 0009-0002-2027-153XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Adrian V. LeeiD· 4 shared Steffi OesterreichiD· 4 shared Alexander Chih-Chieh ChangiD· 3 shared Jagmohan HoodaiD· 2 shared Jie Bin Liu· 2 shared Julia FoldiiD· 2 shared Kanako Mori· 2 shared Marija BalićiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersCancer Biology

Adrian V. LeeORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 19, 2026

Dual HER2/HER3 Targeting with Antibody-Drug Conjugates Reveals a Novel Therapeutic Strategy for HER2-Mutant Lobular Breast Cancer

Jie Bin Liu, Ye Cao, Alexander Chih-Chieh Chang…·Steffi Oesterreich

This study shows HER2 mutations drive HER2/HER3 hyperactivation in ILC, making it sensitive to HER2/HER3-targeting ADCs, and highlights the synergy between T-DXd and P-DXd.

DOI 10.64898/2026.06.18.733194

humanproteomics

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Cancer BiologyBreast Cancer ResearchPeer-reviewedJun 19, 2025

Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer

Alexander Chih-Chieh Chang, Marija Balić, Tanner L. Bartholow…·Steffi Oesterreich

The paper describes the Hope for Others rapid autopsy program for metastatic breast cancer, detailing its protocols, sample collection, and findings on metastasis research and model development.

4 citations

humanclinical cohort / trial

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Cancer BiologybioRxivPreprintFeb 15, 2025

CITEgeist: Accurate deconvolution of spatial transcriptomics with same-slide proteomics reveals midkine as a secreted microenvironment modulator in ESR1 mutant breast cancer.

Alexander Chih-Chieh Chang, Brent Thomas Schlegel, Neil M. Carleton…·Adrian V. Lee

2 citations

humanspatial transcriptomics

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Cancer BiologyEndocrinologyPeer-reviewedAug 27, 2024

ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes

Megan E. Yates, Hunter Waltermire, Kanako Mori…·Steffi Oesterreich

This study shows ER fusion proteins in breast cancer cell lines drive ligand-independent pro-oncogenic pathways, with subtype- and fusion-specific effects.

11 citations

humanbulk RNA-seq

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