BiophysicsbioRxivPreprint
The SAM Domain of EphA2 Inhibits Ligand-Independent Clustering and Activation
Xiaojun Shi, Ryan Lingerak, Pravesh Shrestha…·Adam W. Smith
This study investigates the role of the SAM domain in EphA2, showing it inhibits ligand-independent clustering and kinase activity in both full-length and intracellular domain constructs.