Author

Ruochen Chai

Tsinghua UniversityORCID 0009-0002-5190-3907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jintao LiuiD· 1 shared Ping SheniD· 1 shared Tianmin WangiD· 1 shared Yayun ZhengiD· 1 shared Yihui HeiD· 1 shared Zeqi Xu· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Jintao LiuORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintAug 3, 2023

A reverse-central-dogma pathway underlies ribosome-antibiotic efficacy and accelerates resistance evolution

Yayun Zheng, Ruochen Chai, Zeqi Xu…·Tianmin Wang

This study reveals a reverse-central-dogma pathway by which ribosome antibiotics cause genomic instability and accelerate resistance evolution through transcription-translation coupling disruption.

DOI 10.1101/2023.08.03.551753

bacteria (other)DNA methylation

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