Author

Rema Mandal

Harvard UniversityORCID 0009-0002-9653-5466Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

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Gil AlterovitziD· 1 shared Ning XieiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperGenomics

Gil AlterovitzORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintMay 17, 2025

Unveiling the Biochemical Mechanisms of Aging and the Implications of Oxidative Stress on Cellular Senescence through Multi-Omics Analysis of Fibroblasts

Rema Mandal, Ning Xie, Gil Alterovitz

This study uses multi-omics analysis of human fibroblasts to show that mitochondrial dysfunction and epigenetic changes drive aging, with specific treatments affecting cellular lifespan and metabolic balance.

DOI 10.1101/2025.05.17.654671

humanDNA methylation

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