Nicholas A. Ide

This study uses single-molecule fluorescence microscopy to show that ATP binding enables eIF4F redistribution on mRNA, while ATP hydrolysis is required for eIF4F recycling during PIC loading.

This study uses single-molecule fluorescence imaging to investigate how eIF4F recognizes and activates mRNA caps, revealing allosteric communication and subunit functions in the process.

This study reconstitutes a biochemically active yeast eIF3 complex and shows that eIF3a provides core RNA-binding activity, modulated by interactions with other subunits.