Mirjam Kümmerlin

This paper introduces SPIN-Seq, a method that links DNA sequence with functional properties at the single-molecule level, revealing sequence-dependent transcription factor interactions and RNA polymerase behavior.

The paper introduces tunable fluorogenic DNA probes that enable high-concentration single-molecule fluorescence imaging, overcoming the high concentration barrier and enabling faster and higher-resolution imaging.

This paper introduces modular and tunable single-molecule sensors using DNA origami scaffolds to detect biomolecules with adjustable response windows and specificity.