Author

Michelle M. Butler

Microbiotix (United States)ORCID 0009-0003-2850-4841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 2

Frequent Co-Authors

Terry L. BowliniD· 3 shared Anne J. M. Lenaerts· 2 shared Bernd MeibohmiD· 2 shared Firat KayaiD· 2 shared Gregory T. RobertsoniD· 2 shared Jiuyu LiuiD· 2 shared Matthew D. ZimmermaniD· 2 shared Mercedes Gonzalez JuarreroiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Terry L. BowlinORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 22, 2026

trans-Translation inhibitors that kill M. tuberculosis and pathogenic Non-tuberculous Mycobacteria have a dual mechanism of action

Akanksha Varshney, Ziyi Jia, Gebremichal Gebretsadik…·Kenneth C. Keiler

The paper identifies acylaminooxadiazole derivatives that kill mycobacteria by inhibiting trans-translation and disrupting iron homeostasis.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedSep 30, 2025

Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis

Nathan Peroutka‐Bigus, Michael S. Sherman, Firat Kaya…·Gregory T. Robertson

This study evaluates replacing linezolid with spectinamide MBX-4888A in the Nix-TB regimen for tuberculosis in a mouse model, showing potential for reduced adverse effects.

1 citation

mouseexperimental assay

𝕏 PostBluesky

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedSep 30, 2024

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Allison A. Bauman, Jansy Passiflora Sarathy, Firat Kaya…·Gregory T. Robertson

This study shows that MBX-4888A, a spectinamide, shortens tuberculosis treatment in murine models by improving tissue distribution and working well with rifampin and pyrazinamide.

6 citations

mouseexperimental assay

𝕏 PostBluesky