Author

Matteo Bisardi

Centre National de la Recherche ScientifiqueORCID 0009-0003-7693-5240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Francesco ZamponiiD· 2 shared Martin WeigtiD· 2 shared Sabrina CotognoiD· 2 shared D. Lee· 1 shared John Z. CheniD· 1 shared Leonardo Di BariiD· 1 shared Nobuhiko TokurikiiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Francesco ZamponiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedSep 30, 2024

Understanding epistatic networks in the B1 -lactamases through coevolutionary statistical modeling and deep mutational scanning

John Z. Chen, Matteo Bisardi, D. Lee…·Nobuhiko Tokuriki

The paper uses coevolutionary analysis and deep mutational scanning to study epistatic networks in B1-lactamases, revealing both conserved and specific interactions across homologs.

19 citations

proteomicsdeep learning

𝕏 PostBluesky

Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 26, 2024

Emergent time scales of epistasis in protein evolution

Leonardo Di Bari, Matteo Bisardi, Sabrina Cotogno…·Francesco Zamponi

This paper introduces a data-driven epistatic model of protein evolution that reproduces sequence statistics across different time scales and uncovers the collective nature of epistasis.

35 citationstop 2%

protein sequencestatistical model

𝕏 PostBluesky