Synthetic BiologybioRxivPreprint
Engineering Cybergenetic Cell-Based Therapies
Ching-Hsiang Chang, Asterios Arampatzis, Samuel Balula…·Mustafa Khammash
This paper develops a control-theoretic framework for engineering closed-loop cell-based therapies using nullgram profiling and a digital twin platform to achieve robust regulation of cellular behavior.
DOI 10.64898/2026.01.16.699922