Author

Huai-Yu Liou

TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University gGmbH, Mainz, Germany;ORCID 0009-0004-8237-4977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Barbara SchroersiD· 1 shared Boris StriliciD· 1 shared David Antony SelbyiD· 1 shared Gerrit GrossmanniD· 1 shared Jennifer V. GerbrachtiD· 1 shared Johnny KimiD· 1 shared Maximilian SprangiD· 1 shared Pablo Riesgo-FerreiroiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Barbara SchroersORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintNov 13, 2026

Graph-guided flow matching enables biologically informed prediction at single-cell resolution

Huai-Yu Liou, Maximilian Sprang, David Antony Selby…·Johnny Kim

This paper introduces GFM, a generative framework that predicts single-cell transcriptomes after genetic perturbations using biological knowledge graphs, outperforming existing methods and demonstrating robustness with limited data.

DOI 10.64898/2026.11.12.766125

humanscRNA-seq

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