Author

Todd Pocuca

McMaster UniversityORCID 0009-0004-8532-780XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

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Benjamin M. BolkeriD· 1 shared Guillaume ParéiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Benjamin M. BolkerORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintAug 22, 2026

Design-informed Size Factor Estimation

Todd Pocuca, Guillaume Paré, Benjamin M. Bolker

The paper introduces disize, a normalization method that uses experimental design information to improve size factor estimation in RNA-seq data, showing better accuracy in challenging scenarios.

DOI 10.64898/2026.08.13.744630

bulk RNA-seqstatistical model

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