Author

Jason A. Eshleman

Sangamo BioSciences (United States)ORCID 0009-0004-9371-499XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Jason D. FontenotiD· 2 shared Alex Michael WardiD· 1 shared Alicia GoodwiniD· 1 shared Amy M. PooleriD· 1 shared Andreas Reik· 1 shared Angélique E. Martelli· 1 shared Anthony Chikere· 1 shared Brian Jones· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Jason D. FontenotORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 6, 2024

Potent and selective repression of SCN9A by engineered zinc finger repressors for the treatment of neuropathic pain

Mohammad Samie, Toufan Parman, Mihika Jalan…·Amy M. Pooler

This study demonstrates the use of engineered zinc finger repressors delivered via AAV to reduce SCN9A expression in preclinical models, showing efficacy in reducing neuropathic pain.

3 citations

humanmouse

𝕏 PostBluesky

BioengineeringMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedApr 23, 2024

Epigenetic control of multiple genes with a single lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

Davide Monteferrario, Marion David, Satish Kumar Tadi…·David Fenard

This paper develops a lentiviral system to simultaneously repress multiple genes using zinc finger repressors, showing efficient and long-term gene silencing without DNA editing.

2 citations

humanCRISPR screen

𝕏 PostBluesky