Tomoyuki Wakashima

The paper shows direct CO fixation to acetyl-CoA in archaeal and bacterial Wood-Ljungdahl pathways under hydrogenogenic growth using 13C tracer-based metabolomics.

The paper investigates the evolutionary history of carbon fixation pathways in Thermodesulfobacteriota, finding that their common ancestor had both the Wood-Ljungdahl and reductive glycine pathways, with subsequent gene loss and horizontal gene transfer shaping current diversity.

This study examines how acetate affects CO2 fixation pathways in thermophilic bacteria, showing acetate suppresses the WL pathway and promotes the rTCA cycle in some species.