Author

Severin Walser

University of ZurichORCID 0009-0005-3165-1441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian Beat TschaniD· 1 shared Alexa B. R. McIntyreiD· 1 shared Arpan Kumar RaiiD· 1 shared Diana TintoriD· 1 shared Jana Pachlopnik SchmidiD· 1 shared Katrina MeyeriD· 1 shared Keisuke FujitaiD· 1 shared Lucas PelkmansiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adrian Beat TschanORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJan 4, 2025

Phosphorylation-controlled cohesion of a nuclear condensate regulates mRNA retention

Alexa B. R. McIntyre, Adrian Beat Tschan, Katrina Meyer…·Lucas Pelkmans

The paper shows that phosphorylation controls nuclear speckle cohesion, affecting mRNA retention and that environmental stress alters this process.

34 citationstop 2%

humanbulk RNA-seq

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ImmunologybioRxivPreprintAug 12, 2024

Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation

Tommaso Marchetti, Samantha Milanesi, Diana Tintor…·Jana Pachlopnik Schmid

This study shows that targeted IL-2 treatment reduces hyperinflammation in a perforin-deficient mouse model of HLH by inducing CD8+ T cell exhaustion.

DOI 10.1101/2024.08.12.607544

mouseexperimental assay

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