Matthieu Ranz

The paper integrates ion mobility spectrometry with HDX/MS to better resolve conformational ensembles in DNA oligonucleotides, showing improved kinetic analysis and distinction of non-specific cation binding.

This study identifies RNA G-quadruplexes in the 5'UTR of KRAS mRNA and demonstrates their interaction with hnRNPA1, revealing a post-transcriptional regulatory mechanism.

This paper introduces a framework using hydrogen-deuterium exchange native mass spectrometry to analyze G-quadruplex DNA structures and dynamics, revealing exchange mechanisms and stability relationships.