ImmunologyCellPeer-reviewed
PPARγ downregulation in colonic CD8+ T cells results in epithelial barrier disruption in people with HIV on antiretroviral therapy
Upasana Das Adhikari, Leah M. Froehle, Alexandra N. Pipkin…·Douglas S. Kwon
This study shows that PPARγ downregulation in colonic CD8+ T cells of people with HIV on ART leads to epithelial barrier disruption by promoting lipid uptake and apoptosis.
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