MicrobiologybioRxivPreprint
Dual inhibition of coronavirus Mpro and PLpro enzymes by phenothiazines and their antiviral activity
Katrina L. Forrestall, Eric S. Pringle, Dane C. Sands…·Sultan Darvesh
This paper identifies a phenothiazine urea derivative that inhibits both SARS-CoV-2 Mpro and PLpro proteases and shows broad antiviral activity against multiple human coronaviruses.
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