MicrobiologybioRxivPreprint
Lactate Oxidase (LctO) Acts as a Metabolic Checkpoint Restraining Streptococcus pneumoniae Invasion of Respiratory Epithelial Barriers
DOI 10.64898/2026.07.15.738724
Author
Babek Alibayov
University of Mississippi Medical CenterORCID 0009-0006-2085-6991Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 32 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- MicrobiologyEmerging Microbes & InfectionsPeer-reviewed
Heme-Mediated Selection of Encapsulated Streptococcus pneumoniae in the Lungs by Oxidative Stress
Babek Alibayov, Ana G. Jop Vidal, Landon Murin…·Jorge Eugenio Vidal
This study shows that heme from oxidized hemoglobin promotes the selection of encapsulated Streptococcus pneumoniae in the lungs, linking oxidative stress to pneumococcal pneumonia pathogenesis.
7 citations - MicrobiologybioRxivPreprint
Pneumococcal H2O2 Reshapes Mitochondrial Function and Reprograms Host Cell Metabolism
Anna Scasny, Babek Alibayov, Ngoc Hoang…·Jorge Eugenio Vidal
This study shows pneumococcus-derived H2O2 disrupts host TCA cycle and induces a Warburg-like metabolic shift in lung epithelial cells, enhancing bacterial survival.
DOI 10.1101/2025.05.22.655446 - MicrobiologyDrug Resistance UpdatesPeer-reviewed
Ultrastructural, metabolic and genetic determinants of the acquisition of macrolide resistance by Streptococcus pneumoniae
Xueqing Wu, Babek Alibayov, Xi Xiang…·Jorge Eugenio Vidal
This study identifies molecular and metabolic factors that influence the acquisition of macrolide resistance in Streptococcus pneumoniae through chromosomal and ICE integration.