BiochemistryCellsPeer-reviewed
ANGPTL8 R59W variant influences inflammation through modulating NF-κB pathway under TNFα stimulation
Mohamed Abu‐Farha, Dhanya Madhu, Prashantha Hebbar…·Jehad Ahmed Abubaker
This study shows the ANGPTL8 R59W variant increases TNF and IL7 levels and NF-κB activity through altered binding dynamics.
11 citations