Author

Valentin Do Sacramento

ORCID 0009-0006-3836-627XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amélie WiederkehriD· 2 shared Anna CamusiD· 2 shared Christopher DivsalariD· 2 shared Geoffroy AndrieuxiD· 2 shared Jessica ZuiniD· 2 shared Julia RositzkaiD· 2 shared Laura García‐PratiD· 2 shared Lukas T. JekeriD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Amélie WiederkehrORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 8, 2026

CD117 epitope-shielded hematopoietic stem cell transplantation with toxin-free conditioning and in vivo selection ameliorates β-thalassemia model

Romina Marone, Rosalba Lepore, Kiriaki Paschoudi…·Lukas T. Jeker

This paper demonstrates a method using CD117-blocking antibody and epitope-engineered HSPCs to treat β-thalassemia without myeloablative conditioning.

DOI 10.64898/2026.07.07.736903

humanATAC-seq

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BioengineeringThe Journal of Experimental MedicinePeer-reviewedSep 9, 2023

Epitope Engineered Human Haematopoietic Stem Cells are Shielded from CD123-targeted Immunotherapy

Romina Marone, Emmanuelle Landmann, Anna Devaux…·Lukas T. Jeker

This paper shows that epitope-engineered human hematopoietic stem cells are protected from CD123-targeted immunotherapy while maintaining functionality, offering a strategy for tumor-selective therapy.

40 citationstop 3%

humanexperimental assay

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