Author

Wytze T. F. den Toom

University Medical Center UtrechtORCID 0009-0006-9696-936XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Boudewijn M. T. BurgeringiD· 2 shared Daan M. K. van SoestiD· 2 shared Paulien E. Polderman· 2 shared Sasha De HenauiD· 2 shared Tobias B. DanseniD· 2 shared Janneke P. KeijeriD· 1 shared Johannes LehmanniD· 1 shared Lucas J. M. Bruurs· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Boudewijn M. T. BurgeringORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyFree Radical Biology and MedicinePeer-reviewedJun 29, 2023

Direct quantification of chemogenetic H2O2 production in live human cells.

Wytze T. F. den Toom, Daan M. K. van Soest, Paulien E. Polderman…·Tobias B. Dansen

This paper introduces an assay to directly quantify DAAO-mediated H2O2 production in live human cells and compares it to mitochondrial respiration.

14 citations

humanexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivMar 29, 2023

Mitochondrial H2O2 release does not directly cause genomic DNA damage.

Daan M. K. van Soest, Paulien E. Polderman, Wytze T. F. den Toom…·Tobias B. Dansen

This study shows that mitochondrial H2O2 release does not directly cause genomic DNA damage, as it instead triggers ferroptosis and prevents mutation propagation.

DOI 10.1038/s41467-024-47008-x

humanexperimental assay

𝕏 PostBluesky