Cancer BiologyNAR CancerPeer-reviewed
XPA tumor variants lead to defects in NER that sensitize cells to cisplatin
Alexandra M. Blee, Kaitlyn S Gallagher, Hyun-Suk Kim…·Walter J Chazin
This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.
8 citations