Author

Alexandra M Blee

Department of Biochemistry, Vanderbilt University , Nashville , TN 37205 , USAORCID 0000-0003-4959-5466Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:GWAS / association mapping· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adem Y. DawediD· 1 shared Alice WilliamsoniD· 1 shared Alicia Huerta-Chagoya· 1 shared Alisa Knodle ManningiD· 1 shared Amit R. MajithiaiD· 1 shared Areetha D’SouzaiD· 1 shared Benjamin M. JacobsiD· 1 shared Christina R Troll· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adem Y. DawedORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 24, 2025

An ancestry-enriched HNF4A variant and GP2 reveal distinct mechanisms of type 2 diabetes in exome-wide study of 13,674 cases and 41,024 controls

Sam Hodgson, Vi Bui, Siqi Hu…·Moneeza Kalhan Siddiqui

The paper identifies ancestry-specific T2D risk variants in South Asian populations through exome-wide association study and functional validation.

DOI 10.1101/2025.09.24.25336527

humanwhole-exome sequencing

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Cancer BiologybioRxivJun 29, 2023

XPA tumor variants lead to defects in NER that sensitize cells to cisplatin

Alexandra M Blee, Kaitlyn S Gallagher, Hyun-Suk Kim…·Walter J Chazin

This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.

DOI 10.1093/narcan/zcae013

humanproteomics

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