Hauke Winter

msBayesImpute improves missing value handling in proteomics data by integrating Bayesian factorization and probabilistic dropout models, outperforming existing methods in imputation and normalization.

This study shows that loss of the Y chromosome in lung adenocarcinoma causes epigenetic and transcriptomic changes that increase lineage plasticity and poor clinical outcomes.

This study identifies epigenetic changes in AT2 cells from COPD patients that disrupt IFN and WNT pathways, impairing lung regeneration.

This study evaluates the antifibrotic effects of OTR4120 in lung fibrosis models, showing reduced collagen deposition and fibroblast activation.

Single-cell profiling of lung and bronchial cells places ACE2 mainly in a transient secretory cell state of cultured bronchial epithelium, between goblet and ciliated cells, co-expressing TMPRSS2.