Brittany A. Baker

This study shows that archaeal cell envelopes activate innate immunity via TLR2, unlike bacteria which use multiple PRRs.

The paper analyzes metagenomes and proteomes from geothermal brines to show that archaea and bacteria have highly acidic proteomes and metabolic flexibility in extreme salinity conditions.

This study resolves the phylogeny of extremely halophilic archaea and identifies four independent adaptations to hypersaline environments through phylogenomic analysis and gene transfer mechanisms.