Nancy Villa

This study identifies a ribosomal kinetic checkpoint that governs selective mRNA recruitment through a branched pathway involving productive and arrested states.

This study identifies nanometer-scale RNA-protein clusters (RPCs) formed by eIF4A with cofactors eIF4B and eIF4G, showing their role in enhancing helicase activity through multivalent RNA interactions.

This study identifies a direct interaction between eIF4G and the 40S ribosomal subunit, independent of eIF3, and shows that the eIF4G-RBD enhances translation without requiring m7G cap or mRNA tethering.