BiophysicsPNAS NexusPeer-reviewed
Evolution of hierarchy and irreversibility in theoretical cell differentiation model
Yoshiyuki T Nakamura, Yusuke Himeoka, Nen Saito, Chikara Furusawa
This study shows that hierarchy and irreversibility in cell differentiation emerge naturally in a mathematical model as the number of terminal states increases, without requiring adaptive selection.
4 citations