Author

Nahoko Higashitani

Tohoku UniversityORCID 0009-0007-8025-9029Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Atsushi HigashitaniiD· 3 shared Aoi Kunitomi· 2 shared Kazumasa OhashiiD· 2 shared Kensaku MizunoiD· 2 shared Shinichi SatoiD· 2 shared Shuhei ChibaiD· 2 shared Ahmad Aisha Abu· 1 shared Akira HigashibataiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Atsushi HigashitaniORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintFeb 19, 2026

Microgravity affects the nervous system and aging in C. elegans through reduced tactile stimulation

Atsushi Higashitani, Je-Hyun Moon, Jong-In Hwang…·Akira Higashibata

This study shows microgravity reduces mechanoreceptor gene expression in C. elegans, causing neuromuscular defects and accelerated aging, but physical stimulation in space can reverse these effects.

DOI 10.64898/2026.02.16.706116

C. elegansbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintApr 8, 2025

Actin cytoskeletal remodeling requires the interaction between Solo and LARG in response to substrate stiffness

Aoi Kunitomi, Yusuke Toyofuku, Shuhei Chiba…·Kazumasa Ohashi

The paper investigates the interaction between Solo and LARG in response to substrate stiffness and finds that this interaction is required for actin polymerization.

DOI 10.1101/2025.04.08.647765

experimental assaycell signaling & trafficking

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Cell BiologyMolecular Biology of the CellPeer-reviewedApr 24, 2024

Interaction between Solo and PDZ-RhoGEF is involved in actin cytoskeletal remodeling and response to substrate stiffness

Aoi Kunitomi, Shuhei Chiba, Nahoko Higashitani…·Kazumasa Ohashi

This study identifies PDZ-RhoGEF as an interacting partner of Solo, showing their role in actin cytoskeletal remodeling and response to substrate stiffness.

4 citations

experimental assaycell signaling & trafficking

𝕏 PostBluesky