Author

Thomas Oïffer

Centre National de la Recherche ScientifiqueORCID 0009-0008-0692-9933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Grégory BoëliD· 2 shared Laura MonlezuniD· 2 shared Saravuth Ngo· 2 shared Amin Omairi‐Nasser· 1 shared Anna LipońskaiD· 1 shared Cylia Bouchachi· 1 shared Daniel P. AalbertsiD· 1 shared Farès OusalemiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

Grégory BoëlORCID

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2 papers

Recent·Most cited

MicrobiologyNucleic Acids ResearchPeer-reviewedOct 29, 2025

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli .

Anna Lipońska, Laura Monlezun, Isaac Wilkins…·Grégory Boël

The paper shows that A-rich first six codons in E. coli mRNAs enhance translation initiation and stability, leading to higher protein expression.

10 citations

E. colibulk RNA-seq

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MicrobiologyNature CommunicationsPeer-reviewedJul 26, 2024

Global regulation via modulation of ribosome pausing by the ABC-F protein EttA

Farès Ousalem, Saravuth Ngo, Thomas Oïffer…·Grégory Boël

The paper shows that the ABC-F protein EttA modulates ribosome pausing to regulate protein expression and cell growth by rescuing ribosomes at specific negatively charged amino acid sequences.

24 citations

protein sequenceexperimental assay

𝕏 PostBluesky