Rashidul Islam

This study shows selinexor, an XPO1 inhibitor, reduces viability and induces cell-cycle arrest and apoptosis in testicular germ cell tumors by increasing nuclear p53 and p21.

This study evaluates G4-ligands in TGCTs, finding CX-5461 induces p53-dependent cell death by stabilizing G4s and disrupting RNA polymerase I transcription.

The paper identifies T cell subtypes, particularly Treg and Tfh, in testicular germ cell tumors and suggests their role in tumor progression and immunotherapy.