Molecular BiologybioRxivPreprint
Methylation mimic mutations of progesterone receptor AF1 impair gene-specific regulation through stabilized chromatin interactions
Pheck Khee Lau, Bernett Lee Teck Kwong, Shi Hao Lee…·Valerie C. L. Lin
This study shows that methylation mimic mutations in PR AF1 alter gene-specific regulation by affecting chromatin interactions and coregulator binding in breast cancer cells.
DOI 10.1101/2025.10.23.684277