Comparative analysis of macrophage feeder systems reveals distinct behaviors and key transcriptional shifts in chronic lymphocytic leukemia cells via coculture
Viktoria KohlhasiD, Hendrik Jestrabek, Rocio Rebollido‐RiosiD, Thanh Tung TruongiD, Anton von LomiD, Rebekka Zölzer, Luca D SchreursiD, Duc Pham, Alexander F. vom SteiniD, Michael J. HallekiD, Phuong‐Hien NguyeniD
Abstract
In this brief report, we evaluated various macrophage coculture systems for their CLL-feeding potential, phagocytosis capacity, induction of treatment resistance in CLL cells, and their impact on the transcriptional profiles of CLL cells.
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