Candida auris is rendered non-viable by medium-chain fatty acids
Abstract
The medium-chain fatty acids, octanoic and decanoic acid, found in coconut oil, were fungistatic and decanoic acid was fungicidal against a panel of Candida auris strains, during both planktonic and biofilm growth. The strains were from all four major geographic clades, and some were resistant to several classes of antifungal drugs. These compounds are safe, natural products and could provide a new strategy for skin decolonization and environmental decontamination.
02 /Specification & Classification
Click any tag to browse matching papers- Research Focus
- Approach
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Antifungal efficacy of natural antiseptic products against Candida auris
- Abrogation of pathogenic attributes in drug resistant Candida auris strains by farnesol
V. Srivastava, A. Ahmad·bioRxiv·Oct 4, 2019
- Potassium isomerized linoleate satisfies EPA MB-35-00 for surface disinfection of Candida auris (AR-0381)
D. Changaris, A. L. Carenbauer·bioRxiv·Feb 23, 2021
- Combinations of antifungals to effectively kill drug-resistant Candida auris
S. Jaggavarapu, E. M. Burd, D. S. Weiss·bioRxiv·Sep 26, 2019
- Construction of a drug sensitised Candida auris strain
Mahnoor Hassan, Jessica Furner-Pardoe, … Barry Panaretou·bioRxiv·Dec 28, 2024
- Skin commensal Micrococcus luteus Induces β-defensin-14 in keratinocytes and Enhances IL-17F Responses to Reduce Candida auris Colonization
Shrihari M Ganesh, Shankar Thangamani·bioRxiv·Jun 19, 2026