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Cell BiologybioRxiv
Preprint

Human olfactory organoids as an in vitro model of the olfactory epithelium

Kang‐Hoon KimiD, Ankit Chauhan, Michael A. KohanskiiD, Nithin D. AdappaiD, James N. PalmeriD, Danielle R. ReediD, Noam A. CoheniD, Peihua JiangiD, Hong WangiD, Jennifer E. DouglasiD

Abstract

Abstract/Key PointsO_LIA novel human olfactory epithelial organoid model has been generated from primary cell culture. C_LIO_LIHuman olfactory organoids exhibit immunostaining and gene expression for olfactory cells. C_LIO_LIOlfactory organoids mobilize Ca2+ in response to odorants, a surrogate for neuronal function. C_LI

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