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Systems BiologybioRxiv
Preprint

A Hierarchical Model of the Hypothalamo-Adreno-Pituitary syste

Camilo La Rota, Dan Tudor VuzaiD, Adriana Climescu-HaulicaiD

Abstract

We present a model of the Hypothalamo-Adreno-Pituitary (HPA) system; our approach is hierarchical and biologically sound, reflecting the complexity of the real HPA system. The structure of the conceptual model is based on theoretical frameworks of biological complex systems and its implementation takes advantage of recent hybrid automata modelling and analysis tools, being modular and reflecting parameter and mechanisms uncertainties.

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