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MicrobiologybioRxiv

A flexible and efficient microfluidics platform for the characterization and isolation of novel bacteriophages

A. Sidi MabroukiD, V. Ongenae, D. Claessen, S. Brenzinger, A. BriegeliD

Abstract

Bacteriophages are viruses that infect bacteria. This property makes them highly suitable for varied uses in industry or in the development of the treatment of bacterial infections. However, the conventional methods that are used to isolate and analyze these bacteriophages from the environment are generally cumbersome and time-consuming. Here, we adapted a high-throughput microfluidic setup for long-term analysis of bacteriophage-bacteria interaction and demonstrate isolation of phages from environmental samples.

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