electrophysiology

This paper introduces DcKONN, a deep neural network inspired by biological oscillatory dynamics, and shows it achieves competitive classification accuracy on EEG signals.

The paper shows spinal neurons in mice create a precise kinematic representation of forelimb movement from muscle and tendon afferent input, using two distinct neuron classes.

The paper applies the NaaS methodology to model chemotherapy-induced peripheral neuropathy using human hiPSC neurons, showing drug-specific changes in neuronal activity.

This study investigates the role of the phenylalanine clamp loop in peptide translocation through the anthrax toxin nanopore using electrophysiology and mutant analysis, revealing its critical role in creating a hydrophobic trap.

PhaseICA extracts reoccurring spatiotemporal brain patterns by incorporating phase information, improving the analysis of nonstationary brain activity.

This paper introduces a post-processing framework to improve real-time sleep staging reliability in neuromodulation by combining smoothing techniques and control logic.

This study shows that acute exogenous ketone monoester supplementation reduces cardiac vagal modulation in a dose-dependent manner in healthy adults.

This study confirms that Toxoplasma gondii induces a transient increase in host cell plasma membrane conductance during invasion, suggesting a perforation mechanism for rhoptry protein delivery.

NeuroTest evaluates sensing-capable electrophysiology and neurostimulation systems through a low-cost, open-source benchtop platform to standardize testing and reduce variability across institutions.

The paper identifies a transient membrane conductance increase in host cells induced by Toxoplasma gondii, which precedes invasion and is termed the invasion pore.

The paper introduces ICNet, a deep learning model that accurately simulates neural dynamics in the auditory midbrain across various sounds, including speech.

This study shows that AaH-II selectively activates TTX-S Nav channels, inducing arrhythmias in cardiac tissue, and suggests targeting these channels as an antiarrhythmic strategy.

SCHEPHERD is a universal electrobioreactor platform that enables high-throughput, high-resolution, and programmable DC bioelectric stimulation to study cell behavior and tissue dynamics.

This study shows that pulvinar bursts modulate attention and improve behavioral performance in macaques.

The paper uses single-molecule analysis to show how peptide hydrophobicity, aromaticity, and steric effects govern multi-state translocation through anthrax toxin PA nanopores.

This study evaluates the acute biological response to Utah Optrode Array implantation in macaque cortex, identifying design parameters that minimize tissue damage and improve biocompatibility.

This study investigates how progesterone regulates membrane potential and Ca2+ signaling in human sperm through CatSper and Slo3 channels, revealing feedback mechanisms that control depolarization and repolarization.

This study identifies sex differences in tubuloglomerular feedback dynamics in rodent kidneys, showing males have higher oscillation frequencies but are more prone to TGF loss, leading to increased injury risk.

This study shows that low doses of fentanyl and morphine cause sleep disruption in mice, partially mediated by motor activity but not body temperature.

The paper investigates the effects of polydopamine polymerisation on extracellular electrophysiology of mycelium, finding significant inhibition at 5 mM and 10 mM concentrations.

This study compares cardiorespiratory responses to music in preterm infants and adults, finding similar HRV changes but distinct RSA and coupling patterns indicating different autonomic states.

This study examines how sensorimotor learning affects mirror neuron activity, finding no association between learning rate and pre/post-training motor facilitation levels.

This study evaluates how different types of noise affect motor unit decomposition using HD-sEMG, finding that global noise severely impacts results while localized noise has minimal effects.

This study evaluates how signal degradation affects motor-unit-based gesture recognition using HMI, finding that LDA and DNN perform differently under noise and spatial perturbations.

This study shows that polyamine administration can prolong cardiac repolarization and reduce arrhythmias in a mouse model of SQTS3 caused by Kir2.1M301K mutation.

This study examines how polygenic susceptibility and prenatal immune activation affect neurodevelopment, synaptic density, and behavior in apomorphine-susceptible rats.

This paper introduces a geometry-constrained coupling framework to model cortico-hippocampal dynamics, showing how it captures physiological and pathological activity patterns.

The paper demonstrates that plastic attractors can model flexible rule-based selective attention by forming task-specific synaptic connections and reproducing behavioral and neural findings.

This paper introduces Gel-Amin, a hydrogel that enhances extracellular voltage recordings and signal propagation in 3D cardiac microphysiological systems.

Mice infer stimulus-side priors from recent choices; prior signals are decodable pre-stimulus in 24.0% to 30.2% of 242 brain regions, including early visual and motor areas.