Lipid Membrane Structure and Behavior

This paper introduces a framework to efficiently calculate orientation-dependent lipid dynamics from membrane simulations, showing agreement with experimental data and validating a computational protocol linking simulations to NMR spectroscopy.

This study investigates the lipid environment and conformational dynamics of FcγRIIb and its I232T variant using simulations and assays, finding that they interact with specific lipids rather than lipid rafts and that multivalent IgG complexes may stabilize receptor function.

The paper shows seasonal changes in goldfish retinal neurons' membrane structure and excitability under constant environmental conditions, indicating internal seasonal regulation of CNS activity.

This paper introduces a method to detect permeation events in lipid bilayer simulations, showing permeation frequency and time are independent of force fields and cholesterol reduces permeation.

This study uses microfluidic traps to deform GUVs into non-spherical shapes and observes how FtsZ organization changes in response to membrane geometry.

This study shows that the lipid environment affects dopamine transporter function, specifically influencing amphetamine response in mice.

The paper presents evidence that nanoelectrospray can enable membrane protein complexes to self-assemble in lipid bilayers.

This paper introduces NMFk, an unsupervised machine learning method, to analyze lipid phase separation in MD simulations, identifying roles of lipids, nano-domains, timescales, and physical features.