Microfluidic and Capillary Electrophoresis Applications

This paper introduces a silicon nanodialysis platform with sub-second temporal and 100μm spatial resolution, achieving 100-1000x better performance than traditional microdialysis.

The paper introduces a microfluidic platform for studying C. elegans egg-laying, showing higher throughput and temporal resolution compared to traditional methods.

This paper introduces a reversible PDMS-PS bonding technique for microfluidic devices, enabling stable cell culture and gentle live cell extraction for downstream applications.

This paper introduces a microfluidic transistor that mimics electronic transistor behavior, enabling fluidic circuit design for liquid signal processing and single-particle manipulation.

This paper introduces a low-cost, flame-based method for irreversible PDMS bonding, enabling robust microfluidic and organ-on-chip fabrication with high bonding integrity.

This paper describes a method to directly encapsulate biomolecules in semi-permeable microcapsules using double-emulsions, enabling applications in diagnostics and therapeutics.

This paper introduces a new microfabricated neural probe that enables precise, transient-free sampling of brain extracellular fluid biomarkers in vivo and in vitro.

This paper introduces a microfluidic imaging method for long-term, stable, and parallel live-imaging of C. elegans larval development, enabling observation of previously inaccessible processes.

This paper introduces a microfluidic platform for standardized, sensitive ChIP-Seq on low-input samples, enabling high-throughput and reproducible epigenetic profiling.

This paper describes a valveless microfluidic device for isolating and sequencing single cancer cells, achieving high-quality genome coverage with minimal contamination.

This paper describes a microfluidic transfection device that enables high-throughput mammalian protein expression with controlled culturing and real-time imaging.

Openspritzer is an open hardware system for delivering picolitre volumes with performance comparable to commercial systems, demonstrated in neurobiology applications.