Memory and Neural Mechanisms

This paper introduces MoHA, a model that integrates motivational and visual inputs to generate cognitive maps, enabling adaptive navigation in reinforcement learning agents.

The paper identifies distinct noradrenergic subsystems in the locus coeruleus that dynamically respond to varying levels of social stress, influencing traumatic learning and anxiety.

The paper examines how different cell types in the ventral hippocampus encode anxiety-related information during an anxiety test, finding distinct encoding patterns in granule cells and mossy cells.

The paper investigates how hippocampal neurons track multiple agents during pursuit tasks, finding multiplexed neural maps and semi-orthogonal subspaces for distinguishing agents.

This study shows that serotonin signaling in the rat prefrontal cortex is critical for retrieval-induced forgetting, with specific receptor subtypes modulating memory competition.

The paper shows that human hippocampal neurons encode visual sequences through population-level ring topologies that preserve temporal order.

This paper develops a VAE model with RNNs to study neural mechanisms of perspective transformation between first-person and global map views, finding that temporal sequences and proximal cues are critical.

The paper examines how different contextual exposures during inhibitory avoidance training affect memory strength and precision in male and female rats, finding sex differences in memory precision.

The paper investigates how engrams encode negative-hedonic valence related to alcohol withdrawal in rats, linking these engrams to compulsive alcohol seeking and relapse vulnerability.

This study shows that CA2/3 volume predicts mnemonic stability and episodic memory deficits in human amnesia using representational dissimilarity matrices.

This study examines how rhythmic activity in the dorsal hippocampus of rats changes across different behavioral timescales during a spatial set-shifting task, revealing distinct associations with strategy switching and learning.

The paper validates a Bayesian multilevel learning model for estimating single-trial electrocortical responses during aversive conditioning, showing improved accuracy and handling of missing data.

The paper analyzes biophysical properties of neurons in the rodent medial entorhinal cortex, finding a continuum of depolarizing afterpotential characteristics across cell types.

The paper investigates neural state patterns during memory search, showing hippocampal-neocortical communication facilitates retrieval of event-related information.

The paper shows that environmental enrichment and impoverishment affect cognitive abilities and AP-1 signaling in hippocampal neurons differently depending on cell type.

The paper shows that head direction in mice is driven by both visual and vestibular signals, with visual signals dominating at low speeds and affecting navigational behavior.

The study distinguishes between memory strengthening and generalization, finding that memory generalization, not strengthening, drives depression-like behaviors through mPFC-BNST circuit mechanisms.

This study shows that O-LM interneurons adapt their activity based on navigational reference frames, while VIP interneurons are more influenced by familiarization.

This study investigates synaptic inputs to the retrosplenial cortex, finding that all recorded pyramidal neurons receive input from the anterior thalamic nuclei, with stronger responses compared to other sources.

This study shows the human hippocampus uses episodic memories, not generalised knowledge, to detect prediction errors during learning.

The paper shows that coordinated representational drift in hippocampal CA1 neurons preserves population-level spatial coding stability through translation and rotation in state space, enabling drift correction and stable information readout.

The paper shows that auditory conceptual navigation recruits spatial grid-like computations in the entorhinal-hippocampal system, as evidenced by fMRI and behavioral experiments.

The paper models how egocentric boundary cells in RSC and POR respond to environmental features using different coordinate systems and proposes hypotheses for their functional roles in navigation.

The paper shows that theta oscillations during immobility in the hippocampus support mental exploration of future choices by encoding remote locations, particularly next choices in a working memory task.

The paper identifies VIP interneurons as regulators of hippocampal place cell remapping in novel environments through transient disinhibition and shows their role in spatial learning.

This study reevaluates the synchronicity of hippocampal ripples, finding they are phase-locked within but not between hemispheres, with global time-locking and local phase coupling.

This study identifies sex- and circuit-specific amygdala dysfunction after global cerebral ischemia in mice, linked to enhanced calcium signaling in male survivors.

Operant House is a low-cost, automated platform for operant conditioning testing in mice, revealing early working memory deficits in a Alzheimer's disease model.

This study shows that the entorhinal cortex represents action affordances in conceptual spaces, as reflected in eye movements and neural patterns.

This paper presents a formal model of anxiety disorders based on neural circuit dynamics, identifying key nodes in fear and extinction circuits and their dysfunction in genetic and epigenetic contexts.