Memory and Neural Mechanisms

The paper shows that mouse CA1 neural representations in complex environments reflect predictive navigational histories, with similar compartments represented more similarly across individuals.

The paper introduces an open-source rodent gate system for customizable maze tasks, enabling affordable and robust behavior control.

The paper shows that non-spatial grid-like neural codes in the entorhinal cortex develop with age and correlate with inferential reasoning and intelligence.

This study decodes spatial and valence information from rodent single-unit data using classification techniques, finding sparse distributed coding in the hippocampus and decoding capabilities in multiple medial temporal lobe regions.

The paper investigates sex- and estrous phase-dependent differences in BNSTDL-CRF neuron activity and their role in anxiety-potentiated startle, finding sex-specific effects on fear responses.

The paper determines the minimum number of grid cells needed to replicate place cell firing patterns in eleven enclosures using machine learning.

This study builds a neural network model of the EC-HPC system showing that EC2a supports pattern separation through recurrent inhibition and conjunctive coding, while EC2b/3 supports generalization.

The paper investigates how interictal spikes affect spatial working memory in mice, finding that clustered spikes at reward locations improve performance while dispersed spikes impair it.

SIMPL optimizes neural representations of behaviour by iteratively refining latent variables and tuning curves, revealing more precise spatial encoding than traditional methods.

The paper investigates how time cells in the hippocampus, striatum, and orbitofrontal cortex process temporal information through synchronized activity and theta oscillations during a temporal bisection task.

This study identifies the parasubthalamic nucleus and its Tac1-expressing neurons as critical for active avoidance learning through optogenetic and imaging experiments.

This study examines c-Fos expression in genetically defined amygdala neurons after mild footshock stress, finding differential activity patterns in subregions but no significant transcriptional changes.

This paper investigates how consolidation enhances sequential planning by strengthening neural markers of step-by-step simulation in the brain.

The paper shows that a hierarchical coordinate system in the human entorhinal cortex supports abstract sequence memories, mirroring spatial memory organization.

The paper shows that imbalances between direct and indirect striatal pathways during locomotion are dynamic and task-dependent, linking trajectory representations to behavioral changes.

The paper shows that reactivations in the lateral visual cortex are essential for visual association learning consolidation, with inhibitory neuron manipulation reducing cue-specific reactivations and learning.

The paper identifies a novel long-term threat avoidance behavior influenced by visual experience and mediated by melanopsin-expressing retinal ganglion cells.

The paper uses computational models of complementary learning systems to study memory replay's role in targeted memory reactivation and birdsong development, showing replay drives performance changes during sleep.

This study shows acute aerobic exercise improves eyeblink conditioning in active individuals but not sedentary ones.

This study investigates the role of the claustrum in working memory by analyzing neuronal activity in mice during memory tasks and finds that claustrum inhibition impairs memory performance.

This study shows that single binge-like alcohol exposure impairs fear extinction learning in male adolescent mice but not females, with molecular changes in brain regions linked to PTSD.

The paper shows that task-related neural population activity maintains a conserved low-dimensional organization across different environments and animals, supporting behavioral generalization despite changes in neural representations.

The paper shows that hippocampal repulsion in CA3 and dentate gyrus occurs when internal beliefs differ despite ambiguous or identical visual input during a spatial route-learning task.

This study shows mental schemas enhance cognitive load handling and novel response generation in mice and an artificial neural network.

This study shows rats can transfer spatial distance learning to social distance discrimination, and PPC inactivation does not impair this transfer.

This study investigates how the ventral hippocampus encodes environmental stimuli, finding that vCA1 neurons represent stimulus identity, sensory features, and intensity but not valence.

This study shows that the basolateral amygdala encodes stimulus-specific reward value representations that adapt to internal states and changing reward conditions in mice.

The paper investigates how human medial temporal lobe neurons represent temporal order during memory formation and recall, finding preserved neural codes for temporal positions in both phases.

This study identifies early dysfunction of LEC-projecting dopamine neurons in AD mice, linking it to memory impairments and suggesting therapeutic potential through optogenetics or L-DOPA.

The paper investigates prefrontal cortex (PFC) neuronal activity during a complex spatial working memory task in rodents and finds retrospective mnemonic representations of spatial information during the delay phase, particularly on error trials.