Forensic and Genetic Research

This paper benchmarks genotyping and imputation methods for degraded DNA in forensic applications across diverse populations, finding that ATLAS outperforms conventional tools and that reference panel diversity improves accuracy.

AncestryPainter 2.0 visualizes ancestry composition and admixture history using improved graphical and statistical modules.

The study analyzes Y-chromosome sequencing data from Finland to identify sublineages and geographic patterns within major haplogroups, suggesting dual migration routes for haplogroup N1a1.

This study uses genomic analysis to clarify genetic distinctions among Austroasiatic-speaking populations in northern Thailand, revealing genetic structure within the Mon-Khmer subfamily and highlighting the impact of admixture on certain groups.

The paper quantifies DNA mixture analysis accuracy across 244 human groups, finding higher false inclusion rates in groups with lower genetic diversity and more contributors.

The paper analyzes genetic ancestry of Afro-Puerto Ricans, revealing African origins similar to Lower Guinea and Bight of Biafra, and European origins similar to Iberian, Italian, and Basque populations.

The paper explains the sister repulsion phenomenon in Patterson's f-statistics by proposing a demographic model involving gene flow from an external source.

The paper uses genome analysis to trace the paternal origin of the Aba royal family in Hungary to East Eurasia, linking them to Mongolian ancestry and medieval Hungarian elites.

The paper introduces a statistic to detect population continuity and ghost admixture in ancient genomes by analyzing temporal drift and admixture effects.

This study analyzes ancient genomes from Inka ritual sites to assess genetic diversity and population dynamics in the Andes.

This paper uses CNNs to estimate selection intensity and timing from ancient genomes, improving upon ABC methods and confirming historical selection events in Europe.

The paper examines how inconsistent mtDNA haplogroup nomenclature affects genetic data interpretation and proposes standardized secondary groupings to improve reproducibility and accuracy.

This study investigates the association between ancestral genetic components and complex traits in European biobanks, finding that these components contribute to trait variation and act as confounders.

This study evaluates the calibration and discriminatory power of probabilistic genotyping software in low likelihood ratio ranges using the PROVEDIt dataset.

This study evaluates the performance of qpAdm and f3-statistic in admixture inference under historical and ancient DNA conditions, showing limitations in resolving fine-scale hypotheses but potential for improvement with better f-statistic methods.

The paper presents paleogenomes of three Anatolian equids from the 1st millennium BCE, identifying them as the extinct European wild ass, E. hydruntinus, and revealing genetic relationships and diversity loss.

YHP predicts high-resolution Y-chromosome haplogroups from Y-STR data, enabling efficient male lineage analysis without requiring Y-SNP sequencing.

This study analyzes genetic data from Austronesian and Austroasiatic groups in Vietnam to determine whether language spread was due to demic or cultural diffusion, finding evidence of both.

This study analyzes the genetic profiles of Bronze Age metallurgical individuals to explore genetic heterogeneity and the spread of Siberian ancestry across Northern Eurasia.

The paper compares genetic and oral histories of four Indian populations, finding genetic similarity to other Indian groups but no evidence of additional non-local genetic sources.

This study benchmarks four kinship estimation tools for ancient genomes using simulated pedigrees and finds varying accuracy depending on the tool and SNP count.

DORA is an interactive tool that integrates and visualizes ancient human DNA data with metadata and other layers, enabling analysis of spatiotemporal population genomic data.

The paper reveals a previously unknown genomic lineage in present-day Blackfoot Confederacy individuals and their historic ancestors, showing divergence during the Late Pleistocene.

This study reanalyzes ancient and present-day Siberian genomes to trace the genetic history of Siberian ancestry and its connections to Native Americans and other populations.

The paper analyzes population genetics in the Eastern Highlands of Papua New Guinea using genome-wide data, revealing genetic structure, admixture events, and evidence of female-biased migration linked to the kuru epidemic.

This study evaluates how post-mortem damage and contamination affect imputation performance in ancient DNA, finding that ATLAS improves results for highly damaged genomes and contamination above 5% reduces accuracy.

This study predicts the functional consequences of recent natural selection in Britain by analyzing gene expression changes over 4500 years using ancient and present-day DNA data.

This study analyzes ancient genomes from Bahrain to reveal population history and malaria adaptation, identifying the G6PD Mediterranean mutation's rise in frequency around 5-6 kya.

This study decomposes the contributions of gene flow, genetic drift, and linked selection to allele frequency change over 5,000 years using ancient human DNA datasets.

The paper describes the Allen Ancient DNA Resource (AADR), a curated compendium of ancient human genomes, and reports its growth to over 10,000 individuals with genome-wide data.