Fluid Dynamics and Mixing

This study identifies the distance between fungal biomass and the liquid-air interface as a key factor in pellicle formation in static liquid cultures, showing that reducing this distance accelerates and stabilizes formation.

This paper introduces a tube-in-tube oxygen saturator for precise liquid-phase oxygen control in human cell culture, showing its performance and modeling capabilities.

This study develops a hyphal-dispersion mutant of Aspergillus oryzae with reduced hyphal adhesion and improved enzyme production and bioreactor performance.

This study optimizes stirring strategies for pluripotent stem cell spheroids using CFD and Bayesian optimization, improving suspension stability and reducing mechanical stress.

This paper describes a novel low-shear stress bioreactor for expanding NK-92 cells, showing improved cell growth and viability compared to traditional methods.

This study develops and validates a mathematical model to predict hPSC proliferation in vertical-wheel bioreactors by incorporating shear stress and energy dissipation rate effects, achieving accurate predictions with low error rates.

This paper introduces a low-cost DIY bioreactor system using standard fittings and sensors for microbial cultivation, offering an affordable alternative to commercial bioreactors.

This paper introduces a new flat-sheet membrane bioreactor for controlled gas delivery at low fluxes, validated with oxygen and starch wastewater, showing stable performance over 320 days.

The paper presents a MATLAB simulation of colloid motion in orbital shakers to study particle dynamics in biomedical suspensions.

This paper develops a computational model combining agent-based modeling and computational fluid dynamics to study how rotor speed affects cell growth on microcarriers in bioreactors.