Olfactory and Sensory Function Studies

The paper demonstrates that mammals can perceive temporal structure in odour stimuli at fast timescales, using a novel odour delivery system and behavioural experiments with mice.

The paper explores structure-odor relationships by testing odorants in mice, showing that OSN responses better reflect perceptual classifications than chemical descriptors.

The paper investigates how olfactory cortex pyramidal cells switch between processing sensory and top-down inputs based on respiration phases, revealing distinct current patterns in different layers during inhalation and exhalation.

The paper investigates how mice generalize responses to odorant mixtures by testing models that predict perceptual similarity based on molecular nearest neighbors.

This paper trains an autoencoder to represent odorant chemical space and uses it to predict human olfactory percepts with accuracy comparable to traditional molecular descriptors.

The paper investigates state-dependent changes in olfactory cortical networks by examining the balance of bottom-up and top-down synaptic inputs in freely moving rats.

This study shows that complement 3 signaling via CR3 is necessary for the proper development and refinement of olfactory bulb maps.

The paper identifies unique molecular markers for GC-D+ olfactory sensory neurons and Grueneberg ganglion chemosensory neurons and their target glomeruli in mice.

The paper demonstrates that extrasynaptic glutamatergic signaling in olfactory bulb glomeruli creates a thresholding effect by balancing excitation and inhibition, allowing only strong stimuli to produce an output.

The paper proposes a compressed sensing algorithm in the mammalian main olfactory bulb using computational modeling and electrophysiological data, showing it can efficiently represent odors and adapt to odor mixtures.

The paper investigates age-related olfactory loss by analyzing cytokine levels in human olfactory mucus and their association with olfactory function decline.

The paper predicts perceptual ratings for odorants using natural language semantics and chemoinformatic features, achieving higher accuracy for more descriptors than previous methods.

This study shows that rats can selectively attend to odors amidst competing stimuli, improving odor-guided decisions and sharpening neural representations of odors.

This study investigates the functional role of the cortico-striatal pathway from the piriform cortex to the olfactory tubercle in mice, showing it modulates odor coding through monosynaptic connections.

The paper investigates human olfactory cortical plasticity in aversive associative learning and memory, finding persistent emotional memory and sensory cortical changes contrasted with transient perceptual alterations.

The paper shows opposing spatial gradients of inhibition and neural activity in mouse olfactory cortex, challenging current understanding of odor processing.

The paper identifies a subset of mitral/tufted cells in the olfactory bulb that represent odor concentration changes, enhancing temporal contrast and aiding in navigational decisions.

The paper provides volumetric estimates and neuronal density calculations for the mouse piriform cortex, showing it contains around half a million neurons equally distributed between anterior and posterior regions.