Sleep and Wakefulness Research

The paper examines the activity patterns of specific inhibitory neurons in mice across sleep and wake states, revealing distinct firing dynamics in different behavioral contexts.

This study shows that aged mice show reduced representation of awake/sleep states in local field potential correlations, which can be partially restored with environmental enrichment.

This study compares electroencephalographic signatures of urethane anesthesia and natural sleep-wake states in rats, finding distinct neurophysiological features in urethane that differentiate it from sleep.

The paper investigates behavioral responses to verbal stimuli in sleep stages, finding reactivity in all stages except slow-wave sleep in healthy volunteers.

The paper investigates the role of REM sleep in ocular dominance plasticity in layer 2/3 neurons during the visual critical period using 2-photon calcium imaging in mice.

This study examines how spindle-slow oscillation coupling during sleep relates to memory performance and changes in hippocampal network connectivity after spatial learning.

The paper examines adolescent sleep spindle topography and finds a shift from central to posterior regions for fast spindles, suggesting an anterior-to-posterior maturation pattern.

The paper analyzes REM sleep activity in mice using experimental data and a computational model, finding SWA is prominent in somatosensory areas and linked to reduced cortical responsiveness.

The paper shows that sleep spindles vary continuously across multiple dimensions rather than being strictly divided into slow and fast categories.

This study uses closed-loop acoustic stimulation in mice to explore its effects on hippocampo-thalamo-cortical activity and memory retention during sleep.

This study shows that orexin neurons decode blood glucose dynamics to drive adaptive behavior in mice by tracking glucose gradients and generating neural adaptations.

This study investigates how sleep and sleep deprivation affect memory consolidation and learning, finding that sleep supports memory but not necessarily consolidation's role in new learning.

The paper investigates whether hypocretin/orexin neurons track sensory, cognitive, or motor information by analyzing their activity during sound cues and reward outcomes.

The paper shows that sounds with different meanings affect sleep-associated brain oscillations in mice, with aversive sounds causing more significant changes than neutral ones.

This study shows that sleep disruption can weaken reactivated memories, contrasting with the typical strengthening effect, suggesting memory reactivation can either strengthen or weaken memories based on sleep conditions.

This study examines how different morphine withdrawal paradigms affect sleep behavior in male and female mice, finding sex-specific differences and highlighting the 3-day precipitated withdrawal model as most impactful.

The paper creates a normative sleep spindle database from 772 healthy children and shows age-specific patterns in spindle features across development.

This study shows that targeted memory reactivation during slow wave sleep enhances inferential thinking in a transitive inference task, particularly when applied during the Up-phase of the slow oscillation.

This study shows microglial TNFα regulates brain phosphorylation during sleep, affecting sleep need and duration through synaptic proteins.

This study investigates how acute sleep deprivation affects dissociative experiences and finds that it increases dissociative states through altered EEG rhythms and connectivity.

This paper shows that visuomotor adaptation increases sleep spindle clustering into trains, which correlates with memory retention and spindle-SO coupling.

This study investigates the effects of five hours of sleep deprivation on hippocampal CA1 pyramidal neurons and finds no changes in dendritic length or spine density.

This study examines sepsis-induced instability in brain oscillatory states in a rat model, finding increased state transitions and altered power spectra in EEG data.

This study uses classifiers to predict the effectiveness of closed-loop auditory stimulation during slow-wave sleep based on ongoing neural oscillations.

This study shows that microglial morphology changes with the sleep-wake cycle in a brain region-specific manner, with cortical microglia showing a negative correlation with sleep slow wave activity.

The paper identifies regional differences in cholinergic terminal activity associated with slow-wave activity in specific cortical areas during REM sleep in mice.

This study shows that sleep-dependent memory processing is altered after stroke in rats, with impaired spindle coupling to slow oscillations, and that reducing GABA can restore physiological sleep states and improve recovery.

This study examines how ketamine and sleep stages affect neural complexity in cats using Lempel-Ziv compression, finding dose-dependent changes and differences across brain regions.

This study compares the development of narcoleptic symptoms in male and female orexin-tTA; TetO-DTA mice, finding females develop symptoms faster but both sexes show similar symptoms by week 6.