Topic · Pharmacology · Medicine

Antibiotics Pharmacokinetics and Efficacy

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Pharmacology & Toxicology·Microbiology SpectrumPeer-reviewed·May 15, 2025
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A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data
Noémie Prébonnaud, Alexia Chauzy, Nicolas Grégoire…+3 more authors·Vincent Aranzana‐Climent
Splitting each dose into equal-amount continuous infusions of varying duration, computed by a new algorithm, lets a standard hollow-fiber model reproduce linezolid CSF pharmacokinetics within 20% of target parameters.
3 citations
human·bacteria (other)
·𝕏 Post·Bluesky