Parasitic Infections and Diagnostics

The paper shows that AC2-dependent cAMP signaling mediates encystation in Giardia lamblia in response to stimuli like bile and alkaline pH.

The paper investigates gene expression of Nematocida microsporidia and host responses in Caenorhabditis nematodes, finding conserved transcriptional patterns across hosts and microsporidia species.

This study quantifies and genetically characterizes Giardia duodenalis in river water and sediment, finding higher prevalence in water and identifying additional sub-assemblages in sediment.

This paper identifies GLP4, a GARP-like transcriptional repressor, as a key regulator of encystation initiation in Giardia lamblia by repressing MYB2 and encystation-specific genes during the G1+S phase of the cell cycle.

The paper analyzes global population genomics of two C. hominis subspecies over 500 years, identifying divergence, transmission patterns, and introgression between them.

This paper develops a duplex RT-qPCR assay to detect active Cryptosporidium infections in goats by targeting mRNA transcripts of the COWP gene and 18S rRNA gene.

The paper presents a high-quality, complete reference genome for Cryptosporidium parvum using Oxford Nanopore and Illumina reads, enabling comprehensive genomic studies.

The paper presents a new high-quality genome assembly and annotation for Cryptosporidium parvum IOWA, revealing structural and functional insights into its genome and evolutionary relationships with related species.

This study identifies 396 novel lncRNAs in Cryptosporidium parvum using RNA-seq, showing differential expression and potential regulatory roles.

This paper conducts a GWAS to identify genetic variants associated with symptomatic cryptosporidiosis in infants, finding a strong association with an intronic SNP in PRKCA.

The paper sequences whole genomes of Giardia duodenalis assemblages C and D from dog feces, revealing host-associated gene differences.

The paper uses Nanopore sequencing to generate high-quality genomes and identify structural variants in Giardia isolates, revealing heterozygosity and variant-specific surface proteins.

This study reports the prevalence and genetic diversity of E. bieneusi in Tibetan pigs, identifying novel genotypes and zoonotic potential.