Sexual dimorphism of complement-dependent microglial synaptic pruning and other immune pathways in the developing brain
Daria Prilutsky, Alvin T. Kho, Ariel Feiglin…·Isaac S. Kohane
The paper identifies sex-specific differences in immune-related pathways, particularly complement-dependent microglial synaptic pruning, during brain development and suggests their role in sex differences in neurological disorder vulnerability.