Supramolecular Self-Assembly in Materials

This study explores the sequence-structure relationship in collagen-like peptides, designing new peptides that form diverse quaternary structures beyond triple helices.

This paper designs a tunable protein filament that assembles in response to a peptide ligand and demonstrates its polarized growth and nucleation mechanisms.

This paper develops a supramolecular enzyme-peptide gel platform for localized therapeutic biocatalysis, showing improved retention and efficacy in treating gout.

This paper demonstrates laser-induced control of sol-gel transitions in protein condensates to enable drug loading.

The paper introduces a generalized packing parameter to quantify the morphology of peptide amphiphile micelles, showing good agreement with previous models and highlighting shape and size dependence.

This study develops a method to create aligned peptide nanofibers and shows how their alignment affects hydrogel properties and cell behavior.

SAPdb is a database of experimentally validated peptide nanostructures formed by self-assembly, providing information on chemical modifications, nanostructure types, and experimental conditions.

This paper designs peptides that self-assemble into nanoparticles or sheets based on disulfide bond placement, using computational modeling and microscopy.